Mirtazapine in clinical practice

Frequency of Errors in Clinical Laboratory Practice

  Background and Objective: Laboratory errors are one of the major factors that affect the diagnosis, prognosis, treatment and monitoring in patients.The objective of study is to evaluate the frequency and type of errors in different phases of testing at the Pathology Department of the Shalamar Hospital, Lahore and to evaluate the causes of errors. Methods: This observational study was carrie...

Mirtazapine-induced arthralgia.

AIM With this article, we intend to corroborate the assumed association between mirtazapine and arthralgia by presentation of eight case reports, and we describe a possible mechanism of action. METHODS AND RESULTS The Netherlands Pharmacovigilance Centre Lareb received eight case reports on arthralgia associated with use of mirtazapine. These case reports are presented in short. We also prese...

Clinical Practice Guidelines: Principles for Clinical Practice

S5 print and electronic media where they come across lay guidelines; doctors need to inform the patients regarding available treatment alternatives, their potential harms and benefits, where clinical guidelines work as the best available educative tool. CPGs highlight gaps in known literature where treatment recommendations are not clear cut; hence it helps in identifying areas where future res...

PS213. Pharmacokinetics of mirtazapine and its hydroxylated metabolite in Japanese psychiatric patients treated with mirtazapine

Objectives: Venlafaxine is metabolized by CYP2D6 to O-desmethylvenlafaxine (ODV) and by CYP3A4 to N-desmethylvenlafaxine (NDV). CYP2C19 is also involved in the formation of ODV. The PPIs omeprazole and pantoprazole inhibit CYP2C19 to a different extent. Aim of this study was to investigate the potential effects of both PPIs on serum levels of VEN and ODV. Methods: From a therapeutic drug monito...

Mirtazapine and breast-feeding.